In a statement issued to mark the anniversary of the fight against global hegemony, Iran's Supreme Leader Ayatollah Ali Khamenei stated that the United States is untrustworthy and that changes in Washington's political leadership will not alter its hostile stance toward Tehran. He warned that succumbing to hegemonic enemies will only invite further aggression, and that seeking a compromise with the U.S. in the hope of dropping its hostility is a grave mistake.