U.S. stocks closed mixed on Wednesday, with the Dow Jones Industrial Average and S&P 500 falling, while the Nasdaq rose. This followed U.S. economic data showing Q2 GDP growth revised up by 0.7 percentage points to 2.2%, the Federal Reserve's preferred inflation gauge, the August PCE Price Index, holding steady at 3.4% year-over-year, and September ADP job growth exceeding expectations. However, persistently high long-term bond yields intensified investor concerns. Oil prices also rose due to a lack of progress in U.S.-Iran negotiations regarding the Strait of Hormuz.

Arun Sundaram, an analyst at CFRA Research, noted that high yields might reflect stronger economic growth expectations, partly driven by the AI boom, but investors question whether high yields will impact the stock market. Major European stock markets closed lower after inflation data from France, Germany, and Italy showed surging prices, particularly for gasoline. Fawad Razaqzada, an analyst at Forex.com, stated that Eurozone economic data failed to improve the outlook, with rising inflation and weak sentiment exacerbating stagflation fears.

Specifically, the S&P 500 fell 0.3% to 7,652 points, the Dow Jones Industrial Average dropped 0.9% to 50,906 points, and the Nasdaq rose 0.2% to 26,861 points.