US Vice President JD Vance told Reuters that Iran needs to demonstrate its commitment to not developing nuclear weapons by changing its enrichment program, specifically questioning the need for 60% enriched fuel. Experts suggest this demand for a "meaningful" reduction, rather than complete abandonment, may indicate a shift from Washington's earlier hardline position. The International Atomic Energy Agency reported that Iran had enriched uranium to 60%, below the roughly 90% considered weapons-grade. Meanwhile, Secretary of State Marco Rubio reiterated that Iran cannot have a nuclear weapon, and President Donald Trump warned the war will end through either "the nice way or the not-so-nice way". Iranian President Masoud Pezeshkian stated on Monday that negotiations with Washington were "futile", while Foreign Minister Abbas Araghchi suggested on October 4 that "only negotiations based on justice and fairness" could end the conflict.