Both ARK Space & Defense Innovation ETF (ARKX) and Tema Space Innovators ETF (NASA) charge a management fee of 0.75%, but they have significant differences in their investment strategies and holdings within the commercial space sector. The NASA ETF focuses on global space commercialization, with its largest holding, SpaceX, accounting for 20.14%. In contrast, ARKX emphasizes orbital and sub-orbital aerospace and defense innovation, with SpaceX making up 9% of its portfolio, and it has a broader investment scope, including companies like Deere, Amazon, and AMD.