American Express National Bank has agreed to pay a $350 million penalty to the Office of the Comptroller of the Currency (OCC) after the OCC found that the bank processed approximately $13 billion in suspicious trade-based money laundering (TBML) activities, including accounts related to bank insiders, between June 2014 and May 2025. The OCC's consent order states that American Express failed to effectively maintain its Bank Secrecy Act (BSA) and Anti-Money Laundering (AML) programs. In addition, the Federal Reserve has also taken enforcement action against American Express for similar issues.